Hair Loss Foam (Florida Only)

$180.00

Best for hair regrowth.

MINOXIDIL/MELATONIN/GHK-Cu/TRETINOIN/CAFFEINE SCALP FOAM 5%/0.1%/0.5%/0.025%/2%

Minoxidil acts by shortening the telogen phase and thus causing the quiescent hair follicles to enter prematurely into the anagen phase. The shortening of the telogen phase may induce telogen effluvium after the initiation of minoxidil therapy. Also, minoxidil extends the duration of the anagen phase. Lastly, increased hair length and diameter is a clinical effect of minoxidil.  Minoxidil appears to act on the potassium channels of vascular smooth muscles and hair follicles, which may induce the following effects:

  • Stimulation of the microcirculation near the hair follicles by inducing arteriolar vasodilation, which may cause hair growth
  • Induction of vascular endothelial growth factor (VEGF) expression increases vascularization around the hair follicles, thus contributing to hair growth
  • Activation of the prostaglandin-endoperoxide synthase one which stimulates hair growth
  • Inhibition of androgen effects on the androgen-sensitive hair follicles
  • Direct stimulation of the hair follicles: Minoxidil may act as an ‘epidermal growth factor’ on matrix cells delaying their aging, thus prolonging the duration of the anagen phase, via the activation of the beta-catenin pathway

Apply two pumps (1mL) to the affected area twice area daily.

Category:

Description

According to the objective assessment of the medical investigators, treatment with the cosmetic melatonin solution resulted in significantly improved hair loss in 59.4% and 66.4% of patients after 30 and 90 days.

Topical Melatonin for Treatment of Androgenetic Alopecia

The human peptide GHK (glycyl-l-histidyl-l-lysine) has multiple biological actions, all of which, according to our current knowledge, appear to be health positive. It stimulates blood vessel and nerve outgrowth, increases collagen, elastin, and glycosaminoglycan synthesis, as well as supports the function of dermal fibroblasts. I increase hair growth and thickness, enlarge hair follicle size.

Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data

Topical all-trans-retinoic acid (tretinoin) alone and in combination with 0.5% minoxidil has been tested for the promotion of hair growth in 56 subjects with androgenetic alopecia. After 1 year, the combination of topical tretinoin with 0.5% minoxidil resulted in terminal hair regrowth in 66% of the subjects studied.

Topical tretinoin for hair growth promotion

The beneficial effects of topical application of caffeine in AGA can be attributed to inhibition of phosphodiesterase, improvement in barrier function, follicular penetration, stimulation, and promotion of hair growth.  The proposed mechanism which would counteract DHT-induced miniaturization of the hair follicle includes inhibition of phosphodiesterase by caffeine, which increases cAMP levels in cells and therefore promotes proliferation by stimulating cell metabolism.

Caffeine was found to counteract the suppressive effects of testosterone on hair growth, with a higher hair shaft elongation seen at 120 h after caffeine administration, compared to the control group. This in vitro study thus clearly demonstrates that caffeine is a stimulator of human hair growth which may have importance in the treatment of AGA.

Role of Caffeine in the Management of Androgenetic Alopecia

Related products